By Larry B. Goldstein

Society-sanctioned instructions are precious instruments, yet gaining access to key details could be a daunting activity. This e-book illuminates a transparent route to profitable program of the yank middle Association/American Stroke organization directions. equipped for speedy reference, this new quantity is helping practitioners increase sufferer care.

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Extra resources for A Primer on Stroke Prevention and Treatment: An overview based on AHA/ASA Guidelines

Example text

2) [4]. It should also be emphasized that patients with cardiovascular or peripheral vascular disease have an increased risk of a first stroke. The management of those conditions and their risk factors, which overlap with the ones pertaining to stroke, should also reduce the risk of stroke for such patients. Hypertension This is arguably the most important of the modifiable risk factors, responsible overall for approximately 50% of all strokes, and especially for intracerebral hemorrhages [13].

A recent study from Germany reported that up to 2% of all cryptogenic strokes are caused by Fabry’s [11]. Finally, the evaluation of large genetic databases, as the one from Iceland (DeCode group), found mutations of phosphodiesterase 4D associated with ischemic stroke [12], although this has not been found in studies in other populations. Specific gene therapies have not yet been established, but in some conditions, such as Fabry’s disease, enzyme replacement therapies have been tried. 2) [4].

Quitting smoking is associated with a decreased risk for stroke, which approaches baseline after approximately 5 years from quitting [26,27]. In our patient, smoking cessation would be a major intervention aiming at primary stroke and cardiovascular disease prevention. Hyperlipidemia Several studies have found an increased risk for ischemic stroke in patients with elevated total cholesterol. For example, the Asia Pacific Cohort Studies Collaboration found a 25% increase in ischemic stroke rates for every 1 mmol/L increase in total cholesterol [28].

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A Primer on Stroke Prevention and Treatment: An overview by Larry B. Goldstein
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